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Faculty

Sandra Jill James, Ph.D.

Picture of Picture ofSandra Jill James
  • Professor, College of Medicine, Department of Pediatrics

Sections

  • Developmental Pediatrics

Specialties

  • Basic Scientist

Contact Information

  • Email: JamesJill@uams.edu
    Phone: 479-253-1091
    Address: Arkansas Children's Hospital
    1 Children's Way
    Little Rock, AR 72202

Education

  • M.S., Univ Of California - Los Angel, 1982
  • Ph.D., Univ Of California - Los Angel, 1986
  • U.C. Berkeley, 1964
  • B.S. (Summa Cum Laude), Mills College, 1962

Recent Publications

  • Journal Article, Rose S., Wynne R., Frye RE., Melnyk S., James SJ. Increased susceptibility to ethylmercury-induced mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines. J Toxicol. 2015 :573701.
  • Journal Article, Rose S., Frye RE., Slattery J., Wynne R., Tippett M., Melnyk S., James SJ. Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines. Transl Psychiatry 2015 March; 10(5):e526.
  • Journal Article, Stewart PA., Hyman SL., Schmidt BL., Macklin EA., Reynolds A., Johnson CR., James SJ., Manning-Courtney P. Dietary Supplementation in Children with Autism Spectrum Disorders: Common, Insufficient, and Excessive. J Acad Nutr Diet 2015 August; 115(8):1237-1248 .
  • Journal Article, James SJ., Shpyleva S., Melnyk S., Pavliv O., Pogribny IP. Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 in autism cerebellum. Transl. Psychiatry 2014 October; :e460.
  • Journal Article, Aissa AF., Tryndyak V., de Conti A., Melnyk S., Gomes TD., Bianchi ML., James SJ., Beland FA., Antunes LM., Pogribny IP. Effect of methionine-deficient and methionine-supplemented diets on the hepatic one-carbon and lipid metabolism in mice.. Mol Nutr Food Res. 2014 58:1502-1512.
  • Journal Article, Frye RE., James SJ. Metabolic pathology of autism in relation to redox metabolism. Biomark Med 2014 8:321-30.
  • Journal Article, Rose S., Frye RE., Slattery J., Wynne R., Tippett M., Pavliv O., Melnyk S., James SJ. Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines.. Transl. Psychiatry 2014 April;
  • Journal Article, Rose S., Frye RE., Slattery J., Wynne R., Tippett M., Pavliv O., Melnyk S., James SJ. Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort. . PLoS One 2014 Jan; 9(1)
  • Journal Article, Frye RE., Melnyk S., Fuchs G., Reid T., Jernigan S., Pavliv O., Hubanks A., Gaylor DW., Walters L., James SJ. Effectiveness of methylcobalamin and folinic Acid treatment on adaptive behavior in children with autistic disorder is related to glutathione redox status. Autism Res Treat 2013
  • Journal Article, Hamlin JC., Pauly M., Melnyk S., Pavliv O., Starrett W., Crook TA., James SJ. Dietary intake and plasma levels of choline and betaine in children with autism spectrum disorders. Autism Res Treat. 2013

Recent Grant Awards

  • Autism Metabolic Genomics Laboratory , Jane Botsford Johnson Foundation, 2014-01-01 00:00:00-2017-12-31 00:00:00

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