UAMS Pediatrics

• Professor, College of Medicine, Department of Pediatrics
• Section Chief, Endocrinology & Diabetes
• Vice Chair, Research
• James H. Hamlen, II Endowed Chair in Pediatric Endocrinology

Sections

• Endocrinology & Diabetes

Specialties

• Endocrinology/Metabolism

Contact Information

• Email:	fowlkesjohnl@uams.edu
  Phone:	501-364-1430
  Fax:	501-364-6299
  Address:	Arkansas Children's Hospital
  	1 Children's Way
  	Little Rock, AR 72202

Education

• Graduate, Borger High School, 1977
• B.S., West Texas State University, 1980
• M.D., University Of Texas Health Sci, 1985

Training

• Fellow, Division of Endocrinology, Duke University Medical Center, 1988-1992
• Resident, Internal Medicine, University of Texas Health Science Center at San Antonio, 1986-1988
• Internship, Internal Medicine, University of Texas Health Science Center at San Antonio, 1985-1986

Licensure and Board Certification

• American Board of Medical Specialties, Pediatrics, Pediatric Endocrinology
• American Board of Medical Specialties, Pediatrics, Pediatrics

Recent Honors

• Abstract reviewer for SPR/APS - 2008, 2008
• Abstract reviewer for ASBMR - 2008, 2008
• NIH NAME study section (adhoc), NIH NAME, 2009
• NIH Challenge Grant reviewer (MOSS), NIH Challenge Grant reviewer (MOSS), 2009

Recent Publications

• Journal Article, Wahl, E.C., Aronson, J., Liu, L., Fowlkes J.L., Thrailkill, K.M., Bunn, R.C., Skinner, R.A., Miller, M.J., Cockrell, G.E., Clark, L.M., Ou, Y., Isales, C.M., Badger, T.M., Ronis, M.J., Sims, J., Lumpkin, C.K., Jr. Restoration of regenerative osteoblastogenesis in aged mice; modulation of TNF. Journal of Bone and Mineral Research 2010 25:114-123.
• Journal Article, Wahl, E.C., Aronson, J., Liu, L., Skinner, R.A., Miller, M.J., Cockrell, G.E., Fowlkes J.L., Thailkill, K.M., Bunn, R.C., Ronis, M.J., Lumpkin, C.K., JR. Direct bone formation during distraction osteogenesis does not requre TNF a receptors and elevated serum TNF fails to inhibit bone ofmration in TNFR1 deficient mice. Bone 2010 46:410-477.
• Journal Article, Thrailkill, K.M., Moreau, C.S., Cockrell, G.E., jo, C.H., Bunn, R.C., Morales,-Pozzo, A.E., Lumpkin, C.K., Fowlkes J.L. Disease and gender-specific dysregulation of NGAL and MMP-9 in type 1 diabetes mellitus.. Endocrine 2010 37:336-343.
• Journal Article, Frindik, JP., Fowlkes J.L., Kemp, S., Thrailkill, K., Lippe, B., Dana, K. Stimulant medication use and response to growth hormone therapy: An NCGS database analysis.. Hormone Research 2009 72:160-6.
• Journal Article, Thrailkill, KM., Bunn, C., Fowlkes J.L. Matrix Metalloproteinases: Their potential role in the pathogenesis of diabetic nephropathy.. Endocrine 2009 February; 35(1):1-10.
• Journal Article, Thrailkill, KM., Nimmo, T., Bunn, RC., Cockrell GE., Moreau, CS., Mackintosh, S., Edmondson, RD., Fowlkes J.L. Microalbuminuria in type 1 diabetes mellitus in associated with enhanced excretion of the endocytic multiligand receptors megalin and cubilin.. Diabetes Care 2009 April;
• Journal Article, Fowlkes JL, Bunn RC, Liu L, Wahl EC, Coleman HN, Cockrell GE, Perrien DS, Lumpkin CK, Thrailkill KM. Runt-related transcription factor 2 (RUNX2) and RUNX2-related osteogenic genes are downregulated throughout osteogenesis in type 1 diabetes mellitus. Endocrinology 2007 Dec.
• Journal Article, Fowlkes JL, Bunn RC, Liu L, Wahl EC, Coleman HN, Cockrell GE, Perrien DS, Lumpkin CK, Thrailkill KM. Runt-related transcription factor 2 (RUNX2) and RUNX2-related osteogenic genes are downregulated throughout osteogenesis in type 1 diabetes mellitus. Endocrinology 2007 Dec.
• Journal Article, Harris AM, Hall B, Kriss VM, Fowlkes JL, Kiessling SG. Rabson-Mendenhall syndrome: medullary sponge kidney, a new component. Pediatr Nephrol 2007 Dec; 22(12):2141 - 2144.
• Journal Article, Thrailkill KM, Bunn RC, Moreau CS, Cockrell GE, Simpson PM, Coleman HN, Frindik JP, Kemp SF, Fowlkes JL. Matrix metalloproteinase-2 dysregulation in type 1 diabetes. Diabetes Care 2007 Sep; 30(9):2321 - 2326.

Recent Grant Awards

• The physiology of IGFBP-degrading proteinases in bone, NIH/NIDDK, 5 R01 DK055653-10, 9/1/2005-6/30/2011
• The Insulin and Insulin-like Growth Factor (IGF) Axis in Diabetic Osteopathy, CUMG, 11/1/2009-10/31/2010