UAMS Pediatrics

• Associate Professor, College of Medicine, Department of Pediatrics

Sections

• Neurology

Specialties

• Neurology

Contact Information

• Email:	REFrye@uams.edu
  Phone:	501-364-4662
  Address:	Arkansas Children's Hospital Research Institute
  	13 Children's Way
  	Little Rock, AR 72202

Education

• B.A., C.W. Post of Long Island University, 1986
• M.S., Drexel University, 1991
• Ph.D., Georgetown University, 1998
• M.D., Georgetown University, 1998

Training

• Resident , Pediatrics, Jackson Memorial Hospital, 1998-2000
• Resident, Pediatric Neurology, Children's Hospital Boston, 2000-2003
• Fellow , Behavioral Neurology and Learning Disabilities, Children's Hospital Boston, 2003-2005
• Research Fellow, Psychology, Boston University, 2004-2005

Licensure and Board Certification

• American Board of Medical Specialties, Pediatrics, Pediatrics
• American Board of Medical Specialties, Psychiatry & Neurology, Neurology with Special Qualifications in Child Neurology

Recent Publications

• Journal Article, Rossignol, D., Frye, R.E. Mitrochondrial Dysfunction in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis. Molescular Psychiatry 2012 March ; 17(3):290-314.
• Journal Article, McGraw Fisher, J., Liederman, J., Johnson, J., Lincoln, A., Frye, R.E. A demonstration that task difficulty can confound the interpretation of lateral differences in brain activation between typical and dyslexic readers.. Laterality 2012 May; 17(3):340-60.
• Journal Article, Liederman, J., Fisher, JM., Coty, A., Matthews, G., Frye, R.E., Lincoln, A., Alexander, R. Sex Differences in the Use of Delayed Semantic Context When Listening to Disrupted Speech. Arch Sex Behav 2012 March ; 21
• Journal Article, Frye, R.E. Novel mitochondrial Cytochrombe b gene polymporphisms associated with autism.. Journal of Pediatric Neurology 2012 10:35-40.
• Journal Article, Leon-Carrion, J., Leon-Dominguez, U., Pollonini, L., Wu, M.H., Frye, R.E., Dominguez-Morales, M.R., Zouridakis, G. Synchronization between the anterior and posterior cortex determines consciousness level in patients with traumatic brain injury (TBI). Brain Res. 2012 March; 29
• Journal Article, Frye, R.E., Sequeira, J.M., Quadros, E.V., James, S.J., Rossignol, D. Cerebral folate receptor autoantibodies in autism spectrum disorder.. Molescular Psyciatry 2012 January ; 10
• Journal Article, Rossignol, D., Frye, R.E. A review of research trends in physiological abnormalitieis in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures.. Molescular Psychiatry 2012 April; 17(4):389-401.
• Journal Article, Frye, R.E. Biomarkers of Abnormal Energy Metabolism in Children with Autism Spectrum Disorder.. The North American Journal of Medicine and Science 2012 5; 3:141-7.
• Journal Article, Hasan, K., Walimuni, I., Abid, H., Frye, R., Ewing-Cobb, L., Wolinsky, J., Narayana, P. Multimodal Quantitative Magnetic Resonance Imaging of Thalamic Development and Again Across the Human Lifespan: Implications to Neurodegeneration in Multiple Sclerosis. Journal of Neuroscience 2011 November 16; 31(46):16826-32.
• Journal Article, Rossignol, D., Frye, R.E. Melatonin in Autism Spectrum Disorders: A systematic Review and Meta-analysis. Developmental Medicine and Child Neurology 2011 September ; 53(9):783-92.

Recent Grant Awards

• Frye - ABI Recruitment ABI Funds, ACHRI/ABI, 2011-08-01 00:00:00-2013-06-30 00:00:00
• Frye ABI Recruitment - SAF Funds, ACHRI, 2011-08-01 00:00:00-2014-06-30 00:00:00
• Frye F&A Match, ACHRI, 2012-09-01 00:00:00-2013-06-30 00:00:00
• Frye General Research Account, 2013-01-01 00:00:00-2020-01-31 00:00:00
• Mitochondrial Dysfunction in Autism, Jane Botsford Johnson Foundation, 2013-01-01 00:00:00-2014-12-31 00:00:00
• Prenatal Neuromagnetic Biomarkers for Neurdevlopmental Disorders, ACHRI/ABI, 2012-12-01 00:00:00-2013-08-31 00:00:00